Insider Trading Bull Markets

Transaction Date	Insider	Transaction Type	Number of Shares Transacted
2019-03-11	Flynn James E	Purchase	10000.0
2019-03-11	Flynn James E	Purchase	10000.0
2019-03-11	Flynn James E	Purchase	10000.0
2019-09-04	Sofinnova Capital VII FCPR	Sale	650000.0
2019-09-04	Papiernik Antoine	Sale	650000.0
2019-09-09	PUCKETT DAN	Sale	30467.0
2019-09-09	PUCKETT DAN	Sale	43433.0
2019-09-09	PUCKETT DAN	Sale	1100.0
2019-10-07	MOLL FREDERIC H	Sale	10471.0
2019-10-07	MOLL FREDERIC H	Sale	4529.0
2019-10-10	Zacharias Isaac	Sale	848.0
2019-10-11	Zacharias Isaac	Sale	3152.0
2019-11-11	Zacharias Isaac	Sale	1030.0
2019-11-11	Zacharias Isaac	Sale	2970.0
2019-11-21	Godshall Douglas Evan	Sale	29600.0
2019-11-21	Godshall Douglas Evan	Sale	400.0
2019-12-10	Zacharias Isaac	Sale	1911.0
2019-12-10	Zacharias Isaac	Sale	2089.0
2020-01-10	Zacharias Isaac	Sale	4000.0
2020-01-14	Papiernik Antoine	Sale	42699.0
2020-01-14	Papiernik Antoine	Sale	16048.0
2020-01-14	Sofinnova Capital VII FCPR	Sale	42699.0
2020-01-14	Sofinnova Capital VII FCPR	Sale	16048.0
2020-01-15	Papiernik Antoine	Sale	58333.0
2020-01-15	Sofinnova Capital VII FCPR	Sale	58333.0
2020-01-16	Papiernik Antoine	Sale	57848.0
2020-01-16	Papiernik Antoine	Sale	3611.0
2020-01-16	Sofinnova Capital VII FCPR	Sale	57848.0
2020-01-16	Sofinnova Capital VII FCPR	Sale	3611.0
2020-01-17	Papiernik Antoine	Sale	82383.0
2020-01-17	Papiernik Antoine	Sale	14708.0
2020-01-17	Sofinnova Capital VII FCPR	Sale	82383.0
2020-01-17	Sofinnova Capital VII FCPR	Sale	14708.0
2020-01-21	Papiernik Antoine	Sale	38836.0
2020-01-21	Papiernik Antoine	Sale	53439.0
2020-01-21	Papiernik Antoine	Sale	77175.0
2020-01-21	Sofinnova Capital VII FCPR	Sale	38836.0
2020-01-21	Sofinnova Capital VII FCPR	Sale	53439.0
2020-01-21	Sofinnova Capital VII FCPR	Sale	77175.0
2020-01-22	Sofinnova Capital VII FCPR	Sale	51970.0
2020-01-22	Sofinnova Capital VII FCPR	Sale	2950.0
2020-01-22	Papiernik Antoine	Sale	51970.0
2020-01-22	Papiernik Antoine	Sale	2950.0
2020-02-10	Zacharias Isaac	Sale	3900.0
2020-02-10	Zacharias Isaac	Sale	100.0
2020-02-14	PUCKETT DAN	Sale	12540.0
2020-02-14	PUCKETT DAN	Sale	31204.0
2020-02-14	PUCKETT DAN	Sale	5656.0
2020-02-14	PUCKETT DAN	Sale	600.0
2020-02-18	Godshall Douglas Evan	Sale	16817.0
2020-02-18	Godshall Douglas Evan	Sale	13183.0
2020-03-10	Zacharias Isaac	Sale	1600.0
2020-03-10	Zacharias Isaac	Sale	1500.0
2020-03-10	Zacharias Isaac	Sale	900.0
2020-04-13	Zacharias Isaac	Sale	2490.0
2020-04-13	Zacharias Isaac	Sale	1510.0
2020-05-11	Zacharias Isaac	Sale	1800.0
2020-05-11	Zacharias Isaac	Sale	2200.0
2020-05-15	Godshall Douglas Evan	Sale	6064.0
2020-05-15	Godshall Douglas Evan	Sale	4000.0
2020-05-15	Godshall Douglas Evan	Sale	19936.0
2020-06-01	Sofinnova Capital VII FCPR	Sale	1300.0
2020-06-01	Papiernik Antoine	Sale	1300.0
2020-06-03	Sofinnova Capital VII FCPR	Sale	7996.0
2020-06-03	Papiernik Antoine	Sale	7996.0
2020-06-04	Sofinnova Capital VII FCPR	Sale	4000.0
2020-06-04	Papiernik Antoine	Sale	4000.0
2020-06-05	Sofinnova Capital VII FCPR	Sale	55754.0
2020-06-05	Papiernik Antoine	Sale	55754.0
2020-06-08	Sofinnova Capital VII FCPR	Sale	59879.0
2020-06-08	Papiernik Antoine	Sale	59879.0
2020-06-09	Papiernik Antoine	Sale	10544.0
2020-06-09	Papiernik Antoine	Sale	121543.0
2020-06-09	Papiernik Antoine	Sale	9255.0
2020-06-09	Sofinnova Capital VII FCPR	Sale	10544.0
2020-06-09	Sofinnova Capital VII FCPR	Sale	121543.0
2020-06-09	Sofinnova Capital VII FCPR	Sale	9255.0
2020-06-10	Zacharias Isaac	Sale	4000.0
2020-06-10	Papiernik Antoine	Sale	29729.0
2020-06-10	Sofinnova Capital VII FCPR	Sale	29729.0
2020-07-10	Zacharias Isaac	Sale	4000.0
2020-08-03	Godshall Douglas Evan	Sale	10643.0
2020-08-03	PUCKETT DAN	Sale	8570.0
2020-08-03	Sofinnova Capital VII FCPR	Sale	85549.0
2020-08-03	Papiernik Antoine	Sale	85549.0
2020-08-04	Godshall Douglas Evan	Sale	19357.0
2020-08-04	PUCKETT DAN	Sale	1430.0
2020-08-04	Sofinnova Capital VII FCPR	Sale	33323.0
2020-08-04	Papiernik Antoine	Sale	33323.0
2020-08-05	Sofinnova Capital VII FCPR	Sale	73860.0
2020-08-05	Sofinnova Capital VII FCPR	Sale	35546.0
2020-08-05	Papiernik Antoine	Sale	73860.0
2020-08-05	Papiernik Antoine	Sale	35546.0
2020-08-06	Papiernik Antoine	Sale	46427.0
2020-08-06	Papiernik Antoine	Sale	25295.0
2020-08-06	Sofinnova Capital VII FCPR	Sale	46427.0
2020-08-06	Sofinnova Capital VII FCPR	Sale	25295.0
2020-08-10	Zacharias Isaac	Sale	3800.0
2020-08-10	Zacharias Isaac	Sale	200.0
2020-08-12	Sofinnova Capital VII FCPR	Sale	1300.0
2020-08-12	Papiernik Antoine	Sale	1300.0
2020-08-13	Sofinnova Capital VII FCPR	Sale	13077.0
2020-08-13	Papiernik Antoine	Sale	13077.0
2020-08-17	Sofinnova Capital VII FCPR	Sale	61823.0
2020-08-17	Papiernik Antoine	Sale	61823.0
2020-08-18	Sofinnova Capital VII FCPR	Sale	133922.0
2020-08-18	Papiernik Antoine	Sale	133922.0
2020-08-18	Cahill Colin	Sale	1832.0
2020-08-19	Sofinnova Capital VII FCPR	Sale	18720.0
2020-08-19	Sofinnova Capital VII FCPR	Sale	40720.0
2020-08-19	Sofinnova Capital VII FCPR	Sale	30438.0
2020-08-19	Papiernik Antoine	Sale	18720.0
2020-08-19	Papiernik Antoine	Sale	40720.0
2020-08-19	Papiernik Antoine	Sale	30438.0
2020-08-20	PUCKETT DAN	Sale	5607.0
2020-08-20	Godshall Douglas Evan	Sale	27276.0
2020-08-20	Papiernik Antoine	Sale	33822.0
2020-08-20	Sofinnova Capital VII FCPR	Sale	33822.0
2020-08-21	PUCKETT DAN	Sale	3866.0
2020-08-21	Godshall Douglas Evan	Sale	16750.0
2020-08-21	Papiernik Antoine	Sale	21536.0
2020-08-21	Sofinnova Capital VII FCPR	Sale	21536.0
2020-08-24	Godshall Douglas Evan	Sale	9359.0
2020-08-24	PUCKETT DAN	Sale	527.0
2020-08-24	Papiernik Antoine	Sale	27443.0
2020-08-25	Godshall Douglas Evan	Sale	48761.0
2020-08-25	Papiernik Antoine	Sale	60657.0
2020-08-26	Papiernik Antoine	Sale	23545.0
2020-08-27	Papiernik Antoine	Sale	129312.0
2020-08-27	Papiernik Antoine	Sale	3685.0
2020-08-27	Godshall Douglas Evan	Sale	849.0
2020-09-10	Zacharias Isaac	Sale	1139.0
2020-09-10	Zacharias Isaac	Sale	2861.0
2020-09-14	Papiernik Antoine	Sale	10333.0
2020-09-14	Papiernik Antoine	Sale	49667.0
2020-09-14	Papiernik Antoine	Sale	18528.0
2020-09-15	Papiernik Antoine	Sale	11472.0
2020-09-15	Papiernik Antoine	Sale	27868.0
2020-09-15	Papiernik Antoine	Sale	2132.0
2020-09-18	Papiernik Antoine	Sale	12653.0
2020-09-28	Papiernik Antoine	Sale	17347.0
2020-09-29	Papiernik Antoine	Sale	13256.0
2020-09-30	Papiernik Antoine	Sale	16744.0
2020-10-01	Papiernik Antoine	Sale	1000.0
2020-10-05	Papiernik Antoine	Sale	24587.0
2020-10-06	Papiernik Antoine	Sale	4413.0
2020-10-09	Papiernik Antoine	Sale	1126.0
2020-10-12	Papiernik Antoine	Sale	455.0
2020-10-15	Zacharias Isaac	Sale	400.0
2020-10-15	Zacharias Isaac	Sale	600.0
2020-10-15	Zacharias Isaac	Sale	1038.0
2020-10-15	Zacharias Isaac	Sale	1562.0
2020-10-15	Zacharias Isaac	Sale	400.0
2020-10-15	PUCKETT DAN	Sale	100.0
2020-10-15	PUCKETT DAN	Sale	500.0
2020-10-15	PUCKETT DAN	Sale	600.0
2020-10-15	PUCKETT DAN	Sale	10700.0
2020-10-15	PUCKETT DAN	Sale	100.0
2020-10-16	Papiernik Antoine	Sale	7119.0
2020-10-19	Papiernik Antoine	Sale	9500.0
2020-11-02	PUCKETT DAN	Sale	800.0
2020-11-02	PUCKETT DAN	Sale	820.0
2020-11-02	PUCKETT DAN	Sale	360.0
2020-11-02	PUCKETT DAN	Sale	20.0
2020-11-10	Papiernik Antoi	Sale	2600
2020-11-10	Papiernik Antoi	Sale	30000
2020-11-10	Papiernik Antoi	Sale	30000
2020-11-09	Papiernik Antoi	Sale	30000
2020-11-09	Papiernik Antoi	Sale	11800
2020-11-12	Papiernik Antoi	Sale	17876
2020-11-12	Papiernik Antoi	Sale	30000
2020-11-11	Papiernik Antoi	Sale	27400
2020-11-10	PUCKETT DAN	Sale	10000
2020-11-16	Papiernik Antoi	Sale	26390
2020-11-13	Papiernik Antoi	Sale	30000
2020-11-13	Papiernik Antoi	Sale	3410
2020-11-13	Papiernik Antoi	Sale	8714
2020-11-16	Zacharias Isaac	Sale	653
2020-11-16	Zacharias Isaac	Sale	2449
2020-11-16	Zacharias Isaac	Sale	898
2020-11-18	Papiernik Antoi	Sale	8100
2020-11-17	Papiernik Antoi	Sale	3610
2020-11-18	Godshall Douglas Ev	Sale	3911
2020-11-18	Godshall Douglas Ev	Sale	12220
2020-11-17	Godshall Douglas Ev	Sale	502
2020-11-17	Godshall Douglas Ev	Sale	104673
2020-11-17	Godshall Douglas Ev	Sale	16650
2020-11-17	Godshall Douglas Ev	Sale	8417
2020-11-17	Godshall Douglas Ev	Sale	1903
2020-11-16	Godshall Douglas Ev	Sale	3244
2020-11-16	Godshall Douglas Ev	Sale	31502
2020-11-16	Godshall Douglas Ev	Sale	73517
2020-11-16	Godshall Douglas Ev	Sale	23461
2020-11-23	Papiernik Antoi	Sale	16955
2020-11-23	Papiernik Antoi	Sale	28500
2020-11-20	Papiernik Antoi	Sale	1500
2020-11-20	Papiernik Antoi	Sale	21900
2020-12-01	PUCKETT DAN	Sale	200
2020-12-01	PUCKETT DAN	Sale	200
2020-12-01	PUCKETT DAN	Sale	900
2020-12-01	PUCKETT DAN	Sale	700
2020-12-15	Zacharias Isaac	Sale	4000
2020-12-17	WATKINS FRANK T	Sale	300
2020-12-17	WATKINS FRANK T	Sale	3369
2020-12-17	WATKINS FRANK T	Sale	4331
2020-12-16	WATKINS FRANK T	Sale	3210
2020-12-16	WATKINS FRANK T	Sale	1812
2020-12-16	WATKINS FRANK T	Sale	2978
2021-01-04	PUCKETT DAN	Sale	141
2021-01-04	PUCKETT DAN	Sale	938
2021-01-04	PUCKETT DAN	Sale	921
2021-01-15	Zacharias Isaac	Sale	2600
2021-01-15	Zacharias Isaac	Sale	1100
2021-01-15	Zacharias Isaac	Sale	300
2021-01-20	WATKINS FRANK T	Sale	46
2021-01-20	WATKINS FRANK T	Sale	45
2021-01-20	WATKINS FRANK T	Sale	140
2021-01-20	WATKINS FRANK T	Sale	160
2021-01-20	WATKINS FRANK T	Sale	178
2021-01-20	WATKINS FRANK T	Sale	243
2021-01-20	WATKINS FRANK T	Sale	66
2021-01-20	WATKINS FRANK T	Sale	298
2021-01-20	WATKINS FRANK T	Sale	597
2021-01-20	WATKINS FRANK T	Sale	227
2021-01-19	WATKINS FRANK T	Sale	593
2021-01-19	WATKINS FRANK T	Sale	385
2021-01-19	WATKINS FRANK T	Sale	464
2021-01-19	WATKINS FRANK T	Sale	379
2021-01-19	WATKINS FRANK T	Sale	179
2021-02-01	PUCKETT DAN	Sale	101
2021-02-01	PUCKETT DAN	Sale	1288
2021-02-01	PUCKETT DAN	Sale	611
2021-02-17	WATKINS FRANK T	Sale	19
2021-02-17	WATKINS FRANK T	Sale	10
2021-02-17	WATKINS FRANK T	Sale	45
2021-02-17	WATKINS FRANK T	Sale	721
2021-02-17	WATKINS FRANK T	Sale	585
2021-02-17	WATKINS FRANK T	Sale	397
2021-02-17	WATKINS FRANK T	Sale	223
2021-02-16	WATKINS FRANK T	Sale	20
2021-02-16	WATKINS FRANK T	Sale	31
2021-02-16	WATKINS FRANK T	Sale	128
2021-02-16	WATKINS FRANK T	Sale	124
2021-02-16	WATKINS FRANK T	Sale	154
2021-02-16	WATKINS FRANK T	Sale	221
2021-02-16	WATKINS FRANK T	Sale	461
2021-02-16	WATKINS FRANK T	Sale	502
2021-02-16	WATKINS FRANK T	Sale	359
2021-02-16	Zacharias Isaac	Sale	40
2021-02-16	Zacharias Isaac	Sale	461
2021-02-16	Zacharias Isaac	Sale	400
2021-02-16	Zacharias Isaac	Sale	100
2021-02-16	Zacharias Isaac	Sale	1300
2021-02-16	Zacharias Isaac	Sale	1199
2021-02-16	Zacharias Isaac	Sale	500
2021-02-18	Godshall Douglas Ev	Sale	300
2021-02-18	Godshall Douglas Ev	Sale	1400
2021-02-18	Godshall Douglas Ev	Sale	7039
2021-02-18	Godshall Douglas Ev	Sale	13555
2021-02-18	Godshall Douglas Ev	Sale	13295
2021-02-18	Godshall Douglas Ev	Sale	5911
2021-02-18	Godshall Douglas Ev	Sale	3500
2021-02-22	Papiernik Antoi	Sale	350000
Transaction Date)	Insider	Transaction Type	Number of Shares Transacted