| Transaction Date | Insider | Transaction Type | Number of Shares Transacted |
|---|---|---|---|
| 2019-08-19 | FARRELL PETER C | Purchase | 4681.0 |
| 2019-08-20 | FARRELL PETER C | Purchase | 4432.0 |
| 2019-08-23 | SASSINE ANDY | Purchase | 10000.0 |
| 2019-08-29 | Payne Joseph E | Purchase | 5000.0 |
| 2019-09-12 | Kummerfeld Keith C | Purchase | 500.0 |
| 2019-09-13 | Marquet Magda | Purchase | 2300.0 |
| 2019-12-03 | SASSINE ANDY | Purchase | 10000.0 |
| 2019-12-05 | SASSINE ANDY | Purchase | 5649.0 |
| 2020-06-10 | SASSINE ANDY | Purchase | 5000.0 |
| 2020-06-10 | Payne Joseph E | Purchase | 1000.0 |
| 2020-06-12 | Kummerfeld Keith C | Purchase | 450.0 |
| 2020-09-03 | Chivukula Pad | Sale | 10000.0 |
| 2020-10-01 | Chivukula Pad | Sale | 10000.0 |
| 2020-11-02 | Chivukula Pad | Sale | 10000.0 |
| 2020-12-01 | Chivukula Pad | Sale | 10000 |
| 2020-12-09 | Ultragenyx Pharmaceutical Inc. | Sale | 357745 |
| 2020-12-08 | Ultragenyx Pharmaceutical Inc. | Sale | 442255 |
| 2021-01-04 | Chivukula Pad | Sale | 10000 |
| 2021-02-01 | Chivukula Pad | Sale | 10000 |
| Transaction Date) | Insider | Transaction Type | Number of Shares Transacted |